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Names and identifiers: 

Synonyms:

  • 17-DMAG HCl
  • Alvespimycin HCl
  • 17-Dimethylaminoethylamino-17-demethoxygeldanamycin Hydrochloride

IUPAC Name:

[(4E,6E,9S,10E,12S,13R,16R)-19-[2-(dimethylamino)ethylamino]-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl] carbamate;hydrochloride

RTECS: LX8922000

 

Chemical name: 

17-dimethylaminoethylamino-17-demethoxy-geldanamycin Hydrochloride

Description: 

17-DMAG, also known as Alvespimycin, is a semisynthetic derivate of Geldanamycin, of less hepatotoxicity, improved water solubility.

17-DMAG is an ansamycin antibiotic which binds to Hsp90 (Heat Shock Protein 90) and alters it function.

Molecular weight: 

653.21

17-DMAG-hydrochloride - FER.17D002 - CAS: 467214-21-7

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