Chemdor Chemicals L.L.C.
Safety Data Sheet (SDS)
According to Globally Harmonized System (GHS)
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1
Product identifiers
Product name
:
CHA.80056
Product
Number
:
CHA.80056
Brand
:
Chemdor Chemicals International L.L.C.
REACH No.
:
A registration number is not available for this substance as the
substance or its uses are exempted from registration or the
annual tonnage does not require a registration.
CAS-No.
:
38661-72-2
1.2
Relevant identified uses of the substance or mixture and uses advised against
Identified uses
:
Laboratory chemicals, Manufacture of substances
1.3
Details of the supplier of the safety data sheet
Company
:
Chemdor Chemicals International L.L.C.
Via Monte Rosa 93
I-20149 MILANO
Telephone
:
+39 02 3341 7340
Fax
:
+39 02 3801 0737
E-mail address
:
serviziotecnico@Chemdorgroup.com
1.4
Emergency telephone number
Emergency Phone #
:
800-789-767 (CHEMTREC Italia)
+39-02-4555-7031 (CHEMTREC chiamate
internazionali)
+39 02-6610-1029 (Centro Antiveleni
Niguarda Ca' Granda - Milano)
SECTION 2: Hazards identification
2.1
Classification of the substance or mixture
Classification (REGULATION (EC) No 1272/2008)
Acute toxicity, Category 4
H302
:
Harmful if swallowed.
Acute toxicity, Category 2
H330
:
Fatal if inhaled.
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Skin corrosion, Sub-category 1C
H314
:
Causes severe skin burns and eye
damage.
Serious eye damage, Category 1
H318
:
Causes serious eye damage.
Respiratory sensitisation, Category
H334
:
May cause allergy or asthma
1 symptoms or breathing difficulties if inhaled.
Skin sensitisation, Sub-category 1A
H317
:
May cause an allergic skin reaction.
Long-term (chronic) aquatic hazard,
H413
:
May cause long lasting harmful effects
Category 4 to aquatic life.
2.2
Label elements
Labelling (REGULATION (EC) No 1272/2008)
Hazard pictograms
:
Signal word
:
Danger
Hazard statements
:
H302 Harmful if swallowed.
H314 Causes severe skin burns and eye damage.
H317 May cause an allergic skin reaction.
H330 Fatal if inhaled.
H334 May cause allergy or asthma symptoms or
breathing difficulties if inhaled.
H413 May cause long lasting harmful effects to
aquatic life.
Prevention
:
Precautionary
:
statements P273 Avoid release to the environment.
P280 Wear protective gloves/ protective clothing/
eye protection/ face protection.
Response
:
P301 + P312 IF
SWALLOWED
:
Call a POISON CENTER/
doctor if you feel unwell.
P303 + P361 + P353 IF ON SKIN (or hair)
:
Take off
immediately all contaminated clothing.
Rinse skin with water.
P304 + P340 + P310 IF
INHALED
:
Remove person to
fresh air and keep comfortable for
breathing. Immediately call a POISON
CENTER/ doctor.
P305 + P351 + P338 IF IN
EYES
:
Rinse cautiously with
water for several minutes. Remove contact
lenses, if present and easy to do. Continue
rinsing.
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Reduced Labelling (<= 125 ml)
Hazard pictograms
:
Signal word Danger
Hazard Statements
H330 Fatal if inhaled.
H334 May cause allergy or asthma symptoms or breathing difficulties
if inhaled.
H317 May cause an allergic skin reaction.
H314 Causes severe skin burns and eye damage.
H413 May cause long lasting harmful effects to aquatic life.
Precautionary Statements
P280 Wear protective gloves/ protective clothing/ eye protection/ face
protection.
P303 + P361 + P353 IF ON SKIN (or hair)
:
Take off immediately all contaminated
clothing. Rinse skin with water.
P304 + P340 + P310 IF
INHALED
:
Remove person to fresh air and keep comfortable
for breathing. Immediately call a POISON CENTER/ doctor.
P305 + P351 + P338 IF IN
EYES
:
Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do. Continue
rinsing.
Supplemental Hazard none
Statements
2.3
Other hazards
This substance/mixture contains no components considered to be either persistent,
bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels
of 0.1% or higher.
Ecological information
:
The substance/mixture does not contain components considered to
have endocrine disrupting properties according to REACH Article 57(f) or Commission
Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of
0.1% or higher.
Toxicological information
:
The substance/mixture does not contain components considered to
have endocrine disrupting properties according to REACH Article 57(f) or Commission
Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of
0.1% or higher.
SECTION 3: Composition/information on ingredients
3.1
Substances
EC-No.
:
609-567-4
Components
Chemical name CAS-No. Concentration (% M-Factor, SCL, ATE
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EC-No. w/w)
1,3- 38661-72-2 >= 90 - <= 100 Acute toxicity
Di(isocyanatomethyl)cy 609-567-4 estimate
clohexane
Acute inhalation
toxicity (vapour)
:
0,51 mg/l
SECTION 4: First aid measures
4.1
Description of first aid measures
General advice
:
First aiders need to protect themselves.
Show this safety data sheet to the doctor in
attendance.
If inhaled
:
After inhalation: fresh air. Immediately call in
physician.
If breathing stops
:
immediately apply artificial
respiration, if necessary also oxygen.
In case of skin contact
:
In case of skin contact: Take off immediately all
contaminated clothing. Rinse skin with water/ shower.
Call a physician immediately.
In case of eye contact
:
After eye contact: rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
If swallowed
:
After swallowing: make victim drink water (two
glasses at most), avoid vomiting (risk of perforation).
Call a physician immediately.
Do not attempt to neutralise.
4.2
Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see
section 2.2) and/or in section 11
4.3
Indication of any immediate medical attention and special treatment needed
No data available
SECTION 5: Firefighting measures
5.1
Extinguishing media
Suitable extinguishing
:
Water
media Foam
Carbon dioxide (CO2)
Dry powder
Unsuitable extinguishing
:
For this substance/mixture no limitations of
media extinguishing agents are given.
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5.2
Special hazards arising from the substance or mixture
Specific hazards during
:
Combustible.
fire fighting
Vapours are heavier than air and may spread along
floors.
Forms explosive mixtures with air on intense heating.
Development of hazardous combustion gases or
vapours possible in the event of fire.
Hazardous combustion
:
Carbon oxides
products
Nitrogen oxides (NOx)
5.3
Advice for firefighters
Special protective
:
Stay in danger area only with self-contained breathing
equipment for fire- apparatus. Prevent skin contact by keeping a safe
fighters distance or by wearing suitable protective clothing.
Further information
:
Suppress (knock down) gases/vapours/mists with a
water spray jet.
Prevent fire extinguishing water from contaminating
surface water or the ground water system.
SECTION 6: Accidental release measures
6.1
Personal precautions, protective equipment and emergency procedures
Personal precautions
:
Advice for non-emergency personnel:
Do not breathe vapours, aerosols.
Avoid substance contact.
Ensure adequate ventilation.
Evacuate the danger area, observe emergency
procedures, consult an expert.
For personal protection see
section 8.
6.2
Environmental precautions
Environmental
:
Do not let product enter drains.
precautions
6.3
Methods and material for containment and cleaning up
Methods for cleaning up
:
Cover drains. Collect, bind, and pump off spills.
Observe possible material restrictions (see sections 7
and 10).
Take up carefully with liquid-absorbent material (e.g.
Chemizorb®). Dispose of properly. Clean up affected
area.
6.4
Reference to other sections
For disposal considerations see
section 13.
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SECTION 7: Handling and storage
7.1
Precautions for safe handling
Advice on safe handling
:
Work under hood. Do not inhale substance/mixture.
Avoid generation of vapours/aerosols.
Hygiene measures
:
Immediately change contaminated clothing. Apply
preventive skin protection. Wash hands and face after
working with substance.
For precautions see
section 2.2.
7.2
Conditions for safe storage, including any incompatibilities
Further information on
:
Tightly closed. Keep in a well-ventilated place. Keep
storage conditions locked up or in an area accessible only to qualified or
authorised persons.
Storage class (TRGS 510)
:
6.1A, Combustible, acute toxic Cat. 1 and 2 / very
toxic hazardous materials
Further information on
:
Light sensitive.
storage stability Moisture sensitive.
7.3
Specific end use(s)
Apart from the uses mentioned in
section 1.2 no other specific uses are stipulated
SECTION 8: Exposure controls/personal protection
8.1
Control parameters
Occupational Exposure Limits
8.2
Exposure controls
Personal protective equipment
Eye/face protection
:
Use equipment for eye protection tested and
approved under appropriate government standards
such as NIOSH (US) or EN 166(EU).
Tightly fitting safety goggles
Hand protection
Remarks
:
required
Skin and body protection
:
protective clothing
Respiratory protection
:
required when vapours/aerosols are generated.
Our recommendations on filtering respiratory
protection are based on the following standards
:
DIN
EN 143, DIN 14387 and other accompanying
standards relating to the used respiratory protection
system.
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Recommended
Filter
:
Filter type ABEK
type
:
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory
protective devices are carried out according to the instructions of the producer.
These measures have to be properly documented.
Environmental exposure controls
Advice
:
Do not let product enter drains.
SECTION 9: Physical and chemical properties
9.1
Information on basic physical and chemical properties
Physical state
:
liquid (20 °C, 1.013 hPa)
Color
:
colourless
Odor
:
No data available
Melting point
:
0 °C (1.007 - 1.011 hPa)
Method
:
OECD Test Guideline 102
GLP
:
yes
Boiling point
:
255 °C (1.007 - 1.011 hPa)
Method
:
OECD Test Guideline 103
GLP
:
yes
Flammability
:
No data available
Upper explosion limit /
:
No data available
Upper flammability limit
Lower explosion limit /
:
No data available
Lower flammability limit
Flash point
:
113 °C
Method
:
closed cup
Autoignition temperature
:
390 °C (1.019 hPa)
Method
:
Regulation (EC) No. 440/2008, Annex, A.15
Decomposition
:
No data available
temperature
pH
:
No data available
Viscosity, dynamic
:
No data available
Viscosity, kinematic
:
No data available
Flow time
:
No data available
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Water solubility
:
No data available
Partition coefficient
:
n- : No data available
octanol/water
Vapor pressure
:
0,5 hPa (98 °C)
Relative density
:
1,1 (20 °C)
Method
:
OECD Test Guideline 109
GLP
:
yes
Density
:
1,101 g/cm3 (25 °C)
Method
:
lit.
Relative vapour density
:
No data available
9.2
Other information
Explosives
:
No data available
Oxidizing properties
:
none
Burning rate
:
No data available
Evaporation rate
:
No data available
Molecular weight
:
194,23 g/mol
SECTION 10: Stability and reactivity
10.1
Reactivity
Forms explosive mixtures with air on intense heating.
A range from approx. 15 Kelvin below the flash point is to be rated as critical.
10.2
Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
10.3
Possibility of hazardous reactions
No data available
10.4
Conditions to avoid
Conditions to avoid
:
Avoid moisture.
Strong heating.
10.5
Incompatible materials
Materials to avoid
:
Amines
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Alcohols
Strong oxidizing agents
10.6
Hazardous decomposition products
In the event of fire
:
see section 5
SECTION 11: Toxicological information
11.1
Information on toxicological effects
Acute toxicity
LD50 Oral - Rat - female - 300 - 2.000 mg/kg
(OECD Test Guideline 423)
Acute toxicity estimate Inhalation - Expert judgement - 4 h - 0,51 mg/l - vapour
LD50 Dermal - Rat - male and female - > 5.000 mg/kg
(OECD Test Guideline 402)
Skin corrosion/irritation
Skin - Rabbit
Result
:
Corrosive after 1 to 4 hours of exposure
(OECD Test Guideline 404)
Serious eye damage/eye irritation
Eyes - Rabbit
Result
:
Causes serious eye damage.
Remarks
:
(ECHA)
Respiratory or skin sensitization
Maximisation Test - Guinea pig
Result
:
positive
(OECD Test Guideline 406)
May cause allergic respiratory and skin reactions
Germ cell mutagenicity
Test
Type
:
Ames test
Test system
:
Escherichia coli/Salmonella typhimurium
Metabolic activation
:
with and without metabolic activation
Method
:
OECD Test Guideline 471
Result
:
negative
Test
Type
:
comet assay
Species
:
Rat
Cell type
:
Liver cells
Application
Route
:
Oral
Method
:
OECD Test Guideline 489
Result
:
negative
Test
Type
:
Micronucleus test
Species
:
Rat
Cell type
:
Bone marrow
Application
Route
:
Oral
Method
:
OECD Test Guideline 474
Result
:
negative
Carcinogenicity
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No data available
Reproductive toxicity
No data available
Specific target organ toxicity - single exposure
No data available
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available
11.2
Additional Information
Endocrine disrupting properties
Product
:
CHA.80056
Assessment
:
The substance/mixture does not contain
components considered to have endocrine
disrupting properties according to REACH Article
57(f) or Commission Delegated regulation (EU)
2017/2100 or Commission Regulation (EU)
2018/605 at levels of 0.1% or higher.
burning sensation, Cough, wheezing, laryngitis, Shortness of breath, Headache, Nausea,
Vomiting
To the best of our knowledge, the chemical, physical, and toxicological properties have not
been thoroughly investigated.
SECTION 12: Ecological information
12.1
Toxicity
Components
:
1,3-Di(isocyanatomethyl)cyclohexane
:
Toxicity to
:
EC50 (activated sludge): 17 mg/l
microorganisms Exposure time
:
3 h
Method
:
OECD Test Guideline 209
GLP
:
yes
Ecotoxicology Assessment
Chronic aquatic toxicity
:
May cause long lasting harmful effects to aquatic life.
12.2
Persistence and degradability
Components
:
1,3-Di(isocyanatomethyl)cyclohexane
:
Biodegradability
:
Test
Type
:
aerobic
Inoculum
:
activated sludge, non-adapted
Concentration
:
3,5 mg/l
Result
:
Not readily biodegradable.
Biodegradation
:
3 %
Exposure time
:
28 d
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Method
:
OECD Test Guideline 310
GLP
:
yes
12.3
Bioaccumulative potential
No data available
12.4
Mobility in soil
No data available
12.5
Results of PBT and vPvB assessment
Product
:
CHA.80056
Assessment
:
This substance/mixture contains no components
considered to be either persistent, bioaccumulative
and toxic (PBT), or very persistent and very
bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6
Endocrine disrupting properties
Product
:
CHA.80056
Assessment
:
The substance/mixture does not contain components
considered to have endocrine disrupting properties
according to REACH Article 57(f) or Commission
Delegated regulation (EU) 2017/2100 or Commission
Regulation (EU) 2018/605 at levels of 0.1% or higher.
No data available
12.7
Other adverse effects
No data available
SECTION 13: Disposal considerations
13.1
Waste treatment methods
Product
:
CHA.80056
with the national and local regulations. Leave
chemicals in original containers. No mixing with other
waste. Handle uncleaned containers like the product
itself.
SECTION 14: Transport information
14.1
UN number or ID number
ADR
:
UN 2927
IMDG
:
UN 2927
IATA
:
UN 2927
14.2
UN proper shipping name
ADR
:
TOXIC LIQUID, CORROSIVE, ORGANIC, N.O.S.
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(1,3-Di(isocyanatomethyl)cyclohexane)
IMDG
:
TOXIC LIQUID, CORROSIVE, ORGANIC, N.O.S.
(1,3-Di(isocyanatomethyl)cyclohexane)
IATA
:
Toxic liquid, corrosive, organic, n.o.s.
(1,3-Di(isocyanatomethyl)cyclohexane)
14.3
Transport hazard class(es)
Class Subsidiary risks
ADR
:
6.1 8
IMDG
:
6.1 8
IATA
:
6.1 8
14.4
Packing group
ADR
Packing group
:
II
Classification
Code
:
TC1
Hazard
Identification
:
68
Number
Labels
:
6.1 (8)
Tunnel restriction code
:
(D/E)
IMDG
Packing group
:
II
Labels
:
6.1 (8)
EmS
Code
:
F-A, S-B
IATA (Cargo)
Packing instruction (cargo
:
660
aircraft)
Packing instruction (LQ)
:
Y640
Packing group
:
II
Labels
:
Division 6.1 - Toxic substances, Class 8 - Corrosive
substances
IATA_P (Passenger)
Packing instruction
:
653
(passenger aircraft)
Packing instruction (LQ)
:
Y640
Packing group
:
II
Labels
:
Division 6.1 - Toxic substances, Class 8 - Corrosive
substances
14.5
Environmental hazards
ADR
Environmentally
:
no
hazardous
IMDG
Marine pollutant
:
no
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14.6
Special precautions for user
The transport classification(s) provided herein are for informational purposes only, and solely
based upon the properties of the unpackaged material as it is described within this Safety
Data Sheet. Transportation classifications may vary by mode of transportation, package
sizes, and variations in regional or country regulations.
14.7
Maritime transport in bulk according to IMO instruments
Not applicable for product as supplied.
SECTION 15: Regulatory information
15.1
Safety, health and environmental regulations/legislation specific for the
substance or mixture
REACH - Restrictions on the manufacture, placing
:
Conditions of restriction for the
on the market and use of certain dangerous following entries should be
substances, mixtures and articles (Annex XVII) considered
:
Number on list 3
REACH - Candidate List of Substances of
Very
:
Not applicable
High Concern for Authorisation (Article 59).
Regulation (EU) No 2024/590 on substances that
:
Not applicable
deplete the ozone layer
Regulation (EU) 2019/1021 on persistent organic
:
Not applicable
pollutants (recast)
REACH - List of substances subject to
:
Not applicable
authorisation (Annex XIV)
Seveso
III
:
Directive 2012/18/EU of the H2 ACUTE TOXIC
European Parliament and of the Council
on the control of major-accident hazards
involving dangerous substances.
Other regulations
:
Observe work restrictions regarding maternity protection in accordance to Dir
92/85/EEC or stricter national regulations where applicable.
Take note of Dir 94/33/EC on the protection of young people at work.
15.2
Chemical safety assessment
For this product a chemical safety assessment was not carried out
SECTION 16: Other information
Full text of other abbreviations
ADN - European Agreement concerning the International Carriage of Dangerous Goods by
Inland Waterways; ADR - Agreement concerning the International Carriage of Dangerous
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Goods by Road; AIIC - Australian Inventory of Industrial Chemicals; ASTM - American
Society for the Testing of Materials; bw - Body weight; CLP - Classification Labelling
Packaging Regulation; Regulation (EC) No 1272/2008; CMR - Carcinogen, Mutagen or
Reproductive Toxicant; DIN - Standard of the German Institute for Standardisation; DSL -
Domestic Substances List (Canada); ECHA - European Chemicals Agency; EC-Number -
European Community number; ECx - Concentration associated with x% response; ELx -
Loading rate associated with x% response; EmS - Emergency Schedule; ENCS - Existing and
New Chemical Substances (Japan); ErCx - Concentration associated with x% growth rate
response; GHS - Globally Harmonised System; GLP - Good Laboratory Practice; IARC -
International Agency for Research on Cancer; IATA - International Air Transport Association;
IBC - International Code for the Construction and Equipment of Ships carrying Dangerous
Chemicals in Bulk; IC50 - Half maximal inhibitory concentration; ICAO - International Civil
Aviation Organization; IECSC - Inventory of Existing Chemical Substances in China; IMDG -
International Maritime Dangerous Goods; IMO - International Maritime Organisation; ISHL -
Industrial Safety and Health Law (Japan); ISO - International Organisation for
Standardisation; KECI - Korea Existing Chemicals Inventory; LC50 - Lethal Concentration to
50 % of a test population; LD50 - Lethal Dose to 50% of a test population (Median Lethal
Dose); MARPOL - International Convention for the Prevention of Pollution from Ships; n.o.s. -
Not Otherwise Specified; NO(A)EC - No Observed (Adverse) Effect Concentration; NO(A)EL -
No Observed (Adverse) Effect Level; NOELR - No Observable Effect Loading Rate; NZIoC -
New Zealand Inventory of Chemicals; OECD - Organisation for Economic Co-operation and
Development; OPPTS - Office of Chemical Safety and Pollution Prevention; PBT - Persistent,
Bioaccumulative and Toxic substance; PICCS - Philippines Inventory of Chemicals and
Chemical Substances; (Q)SAR - (Quantitative) Structure Activity Relationship; REACH -
Regulation (EC) No 1907/2006 of the European Parliament and of the Council concerning the
Registration, Evaluation, Authorisation and Restriction of Chemicals; RID - Regulations
concerning the International Carriage of Dangerous Goods by Rail; SADT - Self-Accelerating
Decomposition Temperature; SDS - Safety Data Sheet; SVHC - Substance of Very High
Concern; TCSI - Taiwan Chemical Substance Inventory; TECI - Thailand Existing Chemicals
Inventory; TRGS - Technical Rule for Hazardous Substances; TSCA - Toxic Substances
Control Act (United States); UN - United Nations; vPvB - Very Persistent and Very
Bioaccumulative
Further information
Other information
:
The information is believed to be correct but is not
exhaustive and will be used solely as a guideline,
which is based on current knowledge of the chemical
substance or mixture and is applicable to appropriate
safety precautions for the product. It does not
represent any guarantee of the properties of the
product. Chemdor Corporation and its Affiliates
shall not be held liable for any damage resulting from
handling or from contact with the above product. See
www.Chemdor.com and/or the reverse side of
invoice or packing slip for additional terms and
conditions of sale.
Copyright 2025 Chemdor Co. LLC. License
granted to make unlimited paper copies for internal
use only.
The branding on the header and/or footer of this document may temporarily not visually
match the product purchased as we transition our branding. However, all of the information
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For further information please contact info@chemdor.com.
REG_EU / EN
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Chemdor Chemicals International L.L.C. shall not be held liable for any damage resulting from handling or from contact with the above product.
See www.chemdor.com for additional terms and conditions of sale.
See www.chemdor.com for additional terms and conditions of sale.