Chemdor Chemicals L.L.C.
Safety Data Sheet (SDS)
According to Globally Harmonized System (GHS)
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1
Product identifiers
Product name
:
CHA.82095
Product
Number
:
CHA.82095
Brand
:
Chemdor Chemicals International L.L.C.
Index-No.
:
016-031-00-8
REACH No.
:
01-2119565139-32-xxxx
CAS-No.
:
126-33-0
1.2
Relevant identified uses of the substance or mixture and uses advised against
Identified uses
:
Laboratory chemicals, Manufacture of substances
1.3
Details of the supplier of the safety data sheet
Company
:
Chemdor Chemicals International L.L.C.
Via Monte Rosa 93
I-20149 MILANO
Telephone
:
+39 02 3341 7340
Fax
:
+39 02 3801 0737
E-mail address
:
serviziotecnico@Chemdorgroup.com
1.4
Emergency telephone
Emergency Phone #
:
800-789-767 (CHEMTREC Italia)
+39-02-4555-7031 (CHEMTREC chiamate
internazionali)
+39 02-6610-1029 (Centro Antiveleni
Niguarda Ca' Granda - Milano)
SECTION 2: Hazards identification
2.1
Classification of the substance or mixture
Acute toxicity, (Category 4)
H302
:
Harmful if swallowed.
Reproductive toxicity, (Category
H360FD
:
May damage fertility. May
1B) damage the unborn child.
Specific target organ toxicity -
H373
:
May cause damage to organs
repeated exposure, (Category 2), through prolonged or repeated exposure.
Immune system
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2.2
Label elements
Labelling according Regulation (EC) No 1272/2008
Pictogram
Signal Word Danger
Hazard Statements
H302 Harmful if swallowed.
H360FD May damage fertility. May damage the unborn child.
H373 May cause damage to organs (Immune system) through
prolonged or repeated exposure.
Precautionary Statements
P202 Do not handle until all safety precautions have been read and
understood.
P260 Do not breathe mist or vapors.
P264 Wash skin thoroughly after handling.
P280 Wear protective gloves/ protective clothing/ eye protection/ face
protection.
P301 + P312 IF
SWALLOWED
:
Call a POISON CENTER/ doctor if you feel
unwell.
P308 + P313 IF exposed or concerned
:
Get medical advice/ attention.
Supplemental Hazard none
Statements
Reduced Labeling (<= 125 ml)
Pictogram
Signal Word Danger
Hazard Statements
H360FD May damage fertility. May damage the unborn child.
Precautionary Statements
P202 Do not handle until all safety precautions have been read and
understood.
P280 Wear protective gloves/ protective clothing/ eye protection/ face
protection.
P308 + P313 IF exposed or concerned
:
Get medical advice/ attention.
Supplemental Hazard none
Statements
2.3
Other hazards
This substance/mixture contains no components considered to be either persistent,
bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at
levels of 0.1% or higher.
Ecological information
:
The substance/mixture does not contain components considered to have endocrine
disrupting properties according to REACH Article 57(f) or Commission Delegated regulation
(EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.
Toxicological information
:
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The substance/mixture does not contain components considered to have endocrine
disrupting properties according to REACH Article 57(f) or Commission Delegated regulation
(EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.
SECTION 3: Composition/information on ingredients
3.1
Substances
Synonyms
:
Tetrahydrothiophene 1,1-dioxide
Tetramethylene sulfone
Formula
:
C H O S
4 8 2
Molecular weight
:
120,17 g/mol
CAS-No.
:
126-33-0
EC-No.
:
204-783-1
Index-No.
:
016-031-00-8
Component Classification Concentration
sulpholane; tetrahydrothiophene 1,1-dioxide
CAS-No. 126-33-0 Acute Tox. 4; Repr. 1B; <= 100 %
EC-No. 204-783-1 STOT RE 2; H302,
Index-No. 016-031-00-8 H360FD, H373
For the full text of the H-Statements mentioned in this Section, see
Section 16.
SECTION 4: First aid measures
4.1
Description of first-aid measures
General advice
Show this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation
:
fresh air. Call in physician.
In case of skin contact
In case of skin contact
:
Take off immediately all contaminated clothing. Rinse skin with
water/ shower. Consult a physician.
In case of eye contact
After eye contact
:
rinse out with plenty of water. Call in ophthalmologist. Remove contact
lenses.
If swallowed
After swallowing
:
immediately make victim drink water (two glasses at most). Consult a
physician.
4.2
Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see
section
2.2) and/or in section 11
4.3
Indication of any immediate medical attention and special treatment needed
No data available
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SECTION 5: Firefighting measures
5.1
Extinguishing media
Suitable extinguishing media
Water Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
5.2
Special hazards arising from the substance or mixture
Carbon oxides
Sulfur oxides
Combustible.
Vapors are heavier than air and may spread along floors.
Forms explosive mixtures with air on intense heating.
Development of hazardous combustion gases or vapours possible in the event of fire.
5.3
Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by
keeping a safe distance or by wearing suitable protective clothing.
5.4
Further information
Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire
extinguishing water from contaminating surface water or the ground water system.
SECTION 6: Accidental release measures
6.1
Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel
:
Do not breathe vapors, aerosols. Avoid substance
contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency
procedures, consult an expert.
For personal protection see
section 8.
6.2
Environmental precautions
Do not let product enter drains.
6.3
Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions
(see sections 7 and 10). Take up carefully with liquid-absorbent material (e.g.
Chemizorb®). Dispose of properly. Clean up affected area.
6.4
Reference to other sections
For disposal see
section 13.
SECTION 7: Handling and storage
7.1
Precautions for safe handling
Advice on safe handling
Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands
and face after working with substance.
For precautions see
section 2.2.
7.2
Conditions for safe storage, including any incompatibilities
Storage conditions
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Tightly closed. Keep in a well-ventilated place. Keep locked up or in an area accessible only
to qualified or authorized persons.
Storage class
Storage class (TRGS 510)
:
6.1C: Combustible, acute toxic Cat.3 / toxic compounds or
compounds which causing chronic effects
7.3
Specific end use(s)
Apart from the uses mentioned in
section 1.2 no other specific uses are stipulated
SECTION 8: Exposure controls/personal protection
8.1
Control parameters
Ingredients with workplace control parameters
Derived No Effect Level (DNEL)
Application Area Routes of Health effect Value
exposure
Worker DNEL, dermal Systemic effects
longterm
Worker DNEL, inhalation Systemic effects 9 mg/m3
longterm
Predicted No Effect Concentration (PNEC)
Compartment Value
Fresh water 0,1 mg/l
Sea sediment 0,01 mg/l
Fresh water sediment 0,449 mg/kg
Sea sediment 0,0449 mg/kg
Soil 0,03104 mg/kg
8.2
Exposure controls
Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate
government standards such as NIOSH (US) or EN 166(EU). Safety glasses
Skin protection
This recommendation applies only to the product stated in the safety data sheet,
supplied by us and for the designated use. When dissolving in or mixing with other
substances and under conditions deviating from those stated in EN 16523-1 please
contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet
:
www.kcl.de).
Full contact
Material
:
Chloroprene
Minimum layer thickness
:
0,65 mm
Break through time
:
480 min
Material tested
:
KCL 720 Camapren®
This recommendation applies only to the product stated in the safety data sheet,
supplied by us and for the designated use. When dissolving in or mixing with other
substances and under conditions deviating from those stated in EN 16523-1 please
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contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet
:
www.kcl.de).
Splash contact
Material
:
Latex gloves
Minimum layer thickness
:
0,6 mm
Break through time
:
30 min
Material tested
:
Lapren® (KCL 706 / Chemdor Z677558, Size M)
Body Protection
protective clothing
Respiratory protection
Recommended Filter type
:
Filter A-(P2)
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory
protective devices are carried out according to the instructions of the producer.
These measures have to be properly documented.
Control of environmental exposure
Do not let product enter drains.
SECTION 9: Physical and chemical properties
9.1
Information on basic physical and chemical properties
a) Physical state crystalline
b) Color colorless
c) Odor No data available
d) Melting Melting point/ range
:
20 - 26 °C - lit.
point/freezing point
e) Initial boiling point 104 °C at 0,3 hPa - lit.
and boiling range 285 °C - lit.
f) Flammability (solid, No data available
gas)
g) Upper/lower No data available
flammability or
explosive limits
h) Flash point 177 °C - closed cup
i) Autoignition No data available
temperature
j) Decomposition No data available
temperature
k) pH No data available
l) Viscosity Viscosity, kinematic
:
No data available
Viscosity, dynamic
:
10,34 mPa.s at 30 °C
m) Water solubility 100 g/l at 25 °C - OECD Test Guideline 105
n) Partition coefficient
:
log
Pow
:
< 0 at 20 °C - Bioaccumulation is not expected.
n-octanol/water
o) Vapor pressure 0,035 hPa at 30 °C
p) Density 1,261 g/cm3 at 25 °C - lit.
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Relative density No data available
q) Relative vapor No data available
density
r) Particle No data available
characteristics
s) Explosive properties Not classified as explosive.
t) Oxidizing properties none
9.2
Other safety information
No data available
SECTION 10: Stability and reactivity
10.1
Reactivity
Forms explosive mixtures with air on intense heating.
A range from approx. 15 Kelvin below the flash point is to be rated as critical.
10.2
Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
10.3
Possibility of hazardous reactions
Violent reactions possible with
:
Strong oxidizing agents
10.4
Conditions to avoid
Strong heating.
10.5
Incompatible materials
No data available
10.6
Hazardous decomposition products
In the event of fire
:
see section 5
SECTION 11: Toxicological information
11.1
Information on toxicological effects
Acute toxicity
LD50 Oral - Mouse - 1.900 mg/kg
Remarks
:
(RTECS)
Acute toxicity estimate Oral - 1.900 mg/kg
(ATE value derived from LD50/LC50 value)
Inhalation
:
No data available
LD50 Dermal - Rat - male and female - > 2.000 mg/kg
(Regulation (EC) No. 440/2008, Annex, B.3)
Skin corrosion/irritation
Skin - Rabbit
Result
:
No skin irritation
Remarks
:
(ECHA)
Serious eye damage/eye irritation
Eyes - Rabbit
Result
:
Mild skin irritant
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Remarks
:
(ECHA)
Respiratory or skin sensitization
adjuvant and patch test - Guinea pig
Result
:
negative
(Regulation (EC) No. 440/2008, Annex, B.6)
Germ cell mutagenicity
Test
Type
:
Ames test
Test system
:
Escherichia coli/Salmonella typhimurium
Metabolic activation
:
with and without metabolic activation
Method
:
OECD Test Guideline 471
Result
:
negative
Test
Type
:
In vitro mammalian cell gene mutation test
Test system
:
Mouse lymphoma test
Metabolic activation
:
with and without metabolic activation
Method
:
OECD Test Guideline 476
Result
:
positive
Test
Type
:
In vitro mammalian cell gene mutation test
Test system
:
mouse lymphoma cells
Metabolic activation
:
with and without metabolic activation
Method
:
OECD Test Guideline 490
Result
:
negative
Test
Type
:
Chromosome aberration test in vitro
Test system
:
Chinese hamster lung cells
Metabolic activation
:
with and without metabolic activation
Result
:
negative
Remarks
:
(ECHA)
Test
Type
:
In vitro mammalian cell gene mutation test
Test system
:
Mouse lymphoma test
Metabolic activation
:
with and without metabolic activation
Method
:
OECD Test Guideline 476
Result
:
positive
Carcinogenicity
No data available
Reproductive toxicity
May damage the unborn child.
May damage fertility.
Specific target organ toxicity - single exposure
No data available
Specific target organ toxicity - repeated exposure
May cause damage to organs through prolonged or repeated exposure.
- Immune system
Aspiration hazard
No data available
11.2
Additional Information
Endocrine disrupting properties
Product
:
CHA.82095
Assessment
:
The substance/mixture does not contain
components considered to have endocrine
disrupting properties according to REACH Article
57(f) or Commission Delegated regulation (EU)
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2017/2100 or Commission Regulation (EU)
2018/605 at levels of 0.1% or higher.
Repeated dose toxicity - Rat - male and female - Oral - 13 Weeks - NOAEL (No observed
adverse effect level) - 25 mg/kg
To the best of our knowledge, the chemical, physical, and toxicological properties have not
been thoroughly investigated.
Systemic effects
:
If swallowed
Gastrointestinal disturbance
agitation, spasms
Absorption can result in damage to
:
Kidney
Handle in accordance with good industrial hygiene and safety practice.
SECTION 12: Ecological information
12.1
Toxicity
Toxicity to fish static test LC50 - Oryzias latipes - > 100 mg/l - 96 h
(OECD Test Guideline 203)
Toxicity to daphnia static test EC50 - Daphnia magna (Water flea) - 852 mg/l - 48 h
and other aquatic (OECD Test Guideline 202)
invertebrates
Toxicity to algae static test ErC50 - Pseudokirchneriella subcapitata (algae) - > 1.000
mg/l - 72 h
(OECD Test Guideline 201)
12.2
Persistence and degradability
Biodegradability aerobic - Exposure time 14 d
Result
:
10,1 % - Not readily biodegradable.
(OECD Test Guideline 301C)
12.3
Bioaccumulative potential
No data available
12.4
Mobility in soil
No data available
12.5
Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent,
bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at
levels of 0.1% or higher.
12.6
Endocrine disrupting properties
Product
:
CHA.82095
Assessment
:
The substance/mixture does not contain components
considered to have endocrine disrupting properties
according to REACH Article 57(f) or Commission
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Delegated regulation (EU) 2017/2100 or Commission
Regulation (EU) 2018/605 at levels of 0.1% or higher.
12.7
Other adverse effects
Discharge into the environment must be avoided.
SECTION 13: Disposal considerations
13.1
Waste treatment methods
No data available
SECTION 14: Transport information
14.1
UN number
ADR/RID
:
-
IMDG
:
-
IATA
:
-
14.2
UN proper shipping name
ADR/RID
:
Not dangerous goods
IMDG
:
Not dangerous goods
IATA
:
Not dangerous goods
14.3
Transport hazard class(es)
ADR/RID
:
-
IMDG
:
-
IATA
:
-
14.4
Packaging group
ADR/RID
:
-
IMDG
:
-
IATA
:
-
14.5
Environmental hazards
ADR/RID
:
no IMDG Marine pollutant: no
IATA
:
no
14.6
Special precautions for user
No data available
Further information
Not classified as dangerous in the meaning of transport regulations.
14.7
Maritime transport in bulk according to IMO instruments
Not applicable for product as supplied.
SECTION 15: Regulatory information
15.1
Safety, health and environmental regulations/legislation specific for the
substance or mixture
This material safety data sheet complies with the requirements of Regulation (EC) No.
1907/2006.
Other regulations
Observe work restrictions regarding maternity protection in accordance to Dir 92/85/EEC or
stricter national regulations where applicable.
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Take note of Dir 94/33/EC on the protection of young people at work.
15.2
Chemical Safety Assessment
A Chemical Safety Assessment has been carried out for this substance.
SECTION 16: Other information
Full text of H-Statements
H302 Harmful if swallowed.
H360FD May damage fertility. May damage the unborn child.
H373 May cause damage to organs through prolonged or repeated exposure.
Full text of other abbreviations
ADN - European Agreement concerning the International Carriage of Dangerous Goods
by Inland Waterways; ADR - Agreement concerning the International Carriage of
Dangerous Goods by Road; AIIC - Australian Inventory of Industrial Chemicals; ASTM -
American Society for the Testing of Materials; bw - Body weight; CMR - Carcinogen,
Mutagen or Reproductive Toxicant; DIN - Standard of the German Institute for
Standardisation; DSL - Domestic Substances List (Canada); ECx - Concentration
associated with x% response; ELx - Loading rate associated with x% response; EmS -
Emergency Schedule; ENCS - Existing and New Chemical Substances (Japan); ErCx -
Concentration associated with x% growth rate response; GHS - Globally Harmonized
System; GLP - Good Laboratory Practice; IARC - International Agency for Research on
Cancer; IATA - International Air Transport Association; IBC - International Code for the
Construction and Equipment of Ships carrying Dangerous Chemicals in Bulk; IC50 - Half
maximal inhibitory concentration; ICAO - International Civil Aviation Organization;
IECSC - Inventory of Existing Chemical Substances in China; IMDG - International
Maritime Dangerous Goods; IMO - International Maritime Organization; ISHL - Industrial
Safety and Health Law (Japan); ISO - International Organisation for Standardization;
KECI - Korea Existing Chemicals Inventory; LC50 - Lethal Concentration to 50 % of a
test population; LD50 - Lethal Dose to 50% of a test population (Median Lethal Dose);
MARPOL - International Convention for the Prevention of Pollution from Ships; n.o.s. -
Not Otherwise Specified; NO(A)EC - No Observed (Adverse) Effect Concentration;
NO(A)EL - No Observed (Adverse) Effect Level; NOELR - No Observable Effect Loading
Rate; NZIoC - New Zealand Inventory of Chemicals; OECD - Organization for Economic
Co-operation and Development; OPPTS - Office of Chemical Safety and Pollution
Prevention; PBT - Persistent, Bioaccumulative and Toxic substance; PICCS - Philippines
Inventory of Chemicals and Chemical Substances; (Q)SAR - (Quantitative) Structure
Activity Relationship; REACH - Regulation (EC) No 1907/2006 of the European
Parliament and of the Council concerning the Registration, Evaluation, Authorisation and
Restriction of Chemicals; RID - Regulations concerning the International Carriage of
Dangerous Goods by Rail; SADT - Self-Accelerating Decomposition Temperature; SDS -
Safety Data Sheet; TCSI - Taiwan Chemical Substance Inventory; TECI - Thailand
Existing Chemicals Inventory; TSCA - Toxic Substances Control Act (United States); UN
- United Nations; UNRTDG - United Nations Recommendations on the Transport of
Dangerous Goods; vPvB - Very Persistent and Very Bioaccumulative
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Further information
The information is believed to be correct but is not exhaustive and will be used solely as
a guideline, which is based on current knowledge of the chemical substance or mixture
and is applicable to appropriate safety precautions for the product. It does not represent
any guarantee of the properties of the product. Chemdor Corporation and its
Affiliates shall not be held liable for any damage resulting from handling or from contact
with the above product. See www.Chemdor.com and/or the reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2020 Chemdor Co. LLC. License granted to make unlimited paper copies
for internal use only.
The branding on the header and/or footer of this document may temporarily not visually match
the product purchased as we transition our branding. However, all of the information in the
document regarding the product remains unchanged and matches the product ordered. For
further information please contact info@chemdor.com.
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Chemdor Chemicals International L.L.C. shall not be held liable for any damage resulting from handling or from contact with the above product.
See www.chemdor.com for additional terms and conditions of sale.
See www.chemdor.com for additional terms and conditions of sale.