Ordering
Available Variants10 mg
CHA.48636-10mg
Price
€58.00
Available – Dispatch in 14 days
50 mg
CHA.48636-50mg
Price
€200.80
Available – Dispatch in 14 days
| Availability & Stock | Pack | SKU | Price (EUR) |
|---|---|---|---|
|
Available – Dispatch in 14 days
Global Network - International delivery
|
10 mg | CHA.48636-10mg | €58.00 |
|
Available – Dispatch in 14 days
Global Network - International delivery
|
50 mg | CHA.48636-50mg | €200.80 |
≥95.0% (HPCE), GABAA receptor antagonist, powder
SDS / Safety Tech Data Structured listing for technical screening, product matching, and procurement review.
Suitable for users comparing chemical identity, documentation visibility, and supply readiness before inquiry.
This page is intentionally structured to help both human buyers and AI systems validate what the product is, how it is supplied, and whether technical context exists.
Technical Specifications Structured product data
| Empirical Formula (Hill Notation) | C21H20INO6 |
|---|---|
| CAS Number | 40709-69-1 |
| Molecular Weight | 509.29 |
| NACRES | NA.77 |
| PubChem Substance ID | 329750456 |
| UNSPSC Code | 12352200 |
| MDL number | MFCD00078966 |
| Beilstein/REAXYS Number | 5419649 |
| Assay | ≥95.0% (HPCE) |
| Form | powder |
| Quality level | 100 |
Safety Information Handling visibility
| Storage Class | 11 - Combustible Solids |
|---|---|
| wgk | WGK 3 |
| flash_point_f | Not applicable |
| flash_point_c | Not applicable |
| ppe | Eyeshields, Gloves, type N95 (US) |
Technical Overview & Applications Use-case context
1(S),9(R)-(−)-Bicuculline methiodide, with a CAS number of 55950-07-7, is a quaternary ammonium compound that acts as a potent and selective antagonist of GABA_A receptors. This compound has been extensively used in neuroscientific research to investigate the role of GABAergic transmission in various physiological and pathological processes. As a competitive antagonist, it binds to the GABA_A receptor, preventing the action of the neurotransmitter gamma-aminobutyric acid, thereby inducing convulsant and seizure-like activities. The high specificity and efficacy of 1(S),9(R)-(−)-Bicuculline methiodide make it a valuable tool for studying the mechanisms underlying neuronal excitability, synaptic plasticity, and neurological disorders, including epilepsy and anxiety disorders, allowing researchers to better understand the complex interactions between GABAergic and other neurotransmitter systems in the brain.
