Ordering
Available Variants10 mg
CHA.55620-10mg
Price
€302.40
Available – Dispatch in 14 days
| Availability & Stock | Pack | SKU | Price (EUR) |
|---|---|---|---|
|
Available – Dispatch in 14 days
Global Network - International delivery
|
10 mg | CHA.55620-10mg | €302.40 |
≥95%
SDS / Safety Tech Data Structured listing for technical screening, product matching, and procurement review.
Suitable for users comparing chemical identity, documentation visibility, and supply readiness before inquiry.
This page is intentionally structured to help both human buyers and AI systems validate what the product is, how it is supplied, and whether technical context exists.
Technical Specifications Structured product data
| Empirical Formula (Hill Notation) | C21H16ClF3N4O4 |
|---|---|
| CAS Number | 583840-03-3 |
| Molecular Weight | 480.82 |
| MDL number | MFCD25974057 |
| NACRES | NA.21 |
| Assay | ≥95% |
| Form | powder or crystals |
| Solubility | DMSO: soluble, methanol: soluble |
Safety Information Handling visibility
| Storage Class | 10 - Combustible liquids |
|---|---|
| wgk | WGK 3 |
| flash_point_f | Not applicable |
| flash_point_c | Not applicable |
Technical Overview & Applications Use-case context
Sorafenib N-oxide, with a CAS number of 1431697-81-2, is a significant metabolite of sorafenib, a multikinase inhibitor used in the treatment of various cancers, including renal cell carcinoma and hepatocellular carcinoma. The N-oxide metabolite is formed through the oxidation of sorafenib, primarily by the cytochrome P450 enzyme system. This metabolite has been shown to possess pharmacological activity, contributing to the overall efficacy of sorafenib. Studies have demonstrated that sorafenib N-oxide exhibits inhibitory effects on various kinases, including Raf and vascular endothelial growth factor receptor, which are involved in tumor growth and angiogenesis. Further research is needed to fully elucidate the role of sorafenib N-oxide in the therapeutic effects of sorafenib and its potential as a target for cancer therapy. The understanding of this metabolite is crucial for optimizing sorafenib treatment regimens.
