Octyl β-D-1-thioglucopyranoside

Octyl β-D-1-thioglucopyranoside, with a CAS number of 85618-21-9, is a non-ionic detergent commonly utilized in biochemistry and molecular biology applications. This compound is a derivative of glucose, where the hydroxyl group is replaced by a thiol group, and an octyl chain is attached to the sugar moiety. The resulting molecule exhibits excellent detergent properties, making it suitable for solubilizing and stabilizing membrane proteins. Octyl β-D-1-thioglucopyranoside is often used in protein purification, crystallization, and functional studies, as it can effectively extract proteins from membranes while maintaining their native conformation and activity. Its mild and non-denaturing nature makes it an ideal choice for various biochemical assays and biophysical characterization techniques, allowing researchers to investigate the structure and function of membrane proteins in a more native-like environment.