Sephadex® G-50 Size Exclusion Resin

Sephadex G-50 is a size exclusion resin with a molecular weight cutoff of approximately 30,000 to 50,000 daltons, making it suitable for separating molecules in the range of 1,500 to 30,000 daltons. This resin is composed of dextran beads that are cross-linked with epichlorohydrin, providing a stable and inert matrix for chromatography. Sephadex G-50 is commonly used for desalting and buffer exchange of proteins, peptides, and other biomolecules, as well as for separating small molecules from larger proteins and aggregates. The resin is available in various particle sizes and can be used in a range of chromatography formats, including column chromatography and batch processing. Its high resolution and efficiency make Sephadex G-50 a popular choice for many laboratory applications, including protein purification, peptide separation, and nucleic acid purification.